Magnetic Coil Stimulation of Straight and Bent Amphibian and Mammalian Peripheral Nerve in Vitro: Locus of Excitation

Fig. 1. The electric field and its derivative produced by magnetic stimulation using a figure-of-eight coil. Based on an illustration in Maccabee et al. (1993).
Fig. 2. An experiment to show how the stimulus location changes with the stimulus polarity. Based on an illustration in Maccabee et al. (1993).
Fig. 3. The effect of insulating obstacles on the site of magnetic stimulation. Based on an illustration in Maccabee et al. (1993).
  • It’s an elegant example of how theory suggests an experiment, which once confirmed leads to additional predictions, resulting in even more experiments, and so on; a virtuous cycle.
  • Their illustrations are informative and clear (although I do like the color in my versions). You should be able to get the main point of a scientific paper by merely looking through the figures, and you can do that with Maccabee et al.’s article.
  • In vitro experiments (nerve in a dish) are nice because they strip away all the confounding details of in vivo (nerve in an arm) experiments. You can manipulate the system (say, by adding a couple lucite cylinders) and determine how the nerve responds. Of course, some would say in vivo experiments are better because they include all the complexities of an actual arm. As you might guess, I prefer the simplicity and elegance of in vitro experiments.
  • If you want a coil that stimulates a peripheral nerve below its center, as opposed to off to one side, you can use a four-leaf-coil.
  • Finally, I like this article because Peter Basser and I were the ones who made the theoretical prediction that magnetic stimulation should occur where , not , is maximum (Roth and Basser, “Model of the Stimulation of a Nerve Fiber by Electromagnetic Induction,” IEEE Transactions on Biomedical Engineering, Volume 37, Pages 588–597, 1990). I always love to see my own predictions verified.

--

--

--

Professor of Physics at Oakland University and coauthor of the textbook Intermediate Physics for Medicine and Biology.

Love podcasts or audiobooks? Learn on the go with our new app.

Recommended from Medium

A Slippery Slope Towards Designer Babies?

“Numerical Analysis” Science-Research, January 2022, Week 3 — summary from Astrophysics Data…

Which Industries Can Benefit Most from What Nanotechnology Offers?

doctor with a stethoscope

“Carbon Isotopes” August 2021 — summary from DOE Pages, Astrophysics Data System, Springer Nature…

“Alzheimer’s Disease” Science-Research, March 2022, Week 1 — summary from Europe PMC, PubMed…

DNA Haplogroups are both awesome and ridiculous

“Animal Cell” Science-Research, February 2022 — summary from Europe PMC, PubMed and NCBI Gene

Project trains rats to rescue earthquake victims

Get the Medium app

A button that says 'Download on the App Store', and if clicked it will lead you to the iOS App store
A button that says 'Get it on, Google Play', and if clicked it will lead you to the Google Play store
Brad Roth

Brad Roth

Professor of Physics at Oakland University and coauthor of the textbook Intermediate Physics for Medicine and Biology.

More from Medium

Indispensable Electronics Manufacturer

Indispensable Electronics Manufacturer

Containers In Kubernetes — Day 08

Windows Server 2019 Installation & Setup in Fusion!

Windows Subsystem for Linux, Flaw or Feature?